REDUCE - REDuction of UnCertain Edges
REDUCE is an algorithm for optimal design of gene knock-out (KO) for the purpose of gene regulatory network (GRN) inference. Please refer to our manuscript entitled "Optimal design of gene knock-out experiments for gene regulatory network inference" for more details regarding the algorithm. The archive zip file provides MATLAB scripts for REDUCE.
Prerequisites: MATLAB 2014b (also tested on Octave 3.2.4), Python 2.7
Last Update
Date of last modification: 08.10.2015
License
Redistribution and use in source and binary forms, with or without modification, are permitted provided agreeing to the Simplified BSD Style License.
Read about Simplified BSD Style License at external page http://www.opensource.org/licenses/bsd-license.php
Download & Installation
Download & unzip the Download REDUCE.zip (ZIP, 22 KB)
Please use the following reference when using REDUCE
- Ud-Dean, SMM., and Gunawan, R. Optimal design of gene knock-out experiments for gene regulatory network inference. Bioinformatics 32 (6): 875-883 (2016). external page abstract
Acknowledgement
This work is supported by funding from Swiss National Science Foundation.