Conference Presentations
93. N. Papili Gao, T. Hartmann and R. Gunawan. Clustering and lineage inference in single cell transcriptional analysis of cell differentiation, presented at the 10th Annual RECOMB/ISCB Conference on Regulatory and Systems Genomics, New York, NY, 19 November 2017. (poster)
92. S. Ravi, M. Garcia-Albornoz and R. Gunawan. Bridging transcriptomics and phenomics in the analysis of human ageing, presented at the Biology of Ageing II, Singapore, 15 November 2017. (poster)
91. H. Noh and R. Gunawan. Identifying molecular targets of drugs using an integrative network analysis of protein-protein and protein-DNA and transcriptomics data, presented at AIChE Annual Meeting, Minneapolis, MN, 2 November 2017. (talk)
90. N. Papili Gao and R. Gunawan. A two-state model-based cell clustering and network inference for single-cell gene expression data, presented at AIChE Annual Meeting, Minneapolis, MN, 31 October 2017. (talk)
89. R. Gunawan and S. Hutter. Model misspecifications in Metabolic Flux Analysis: Biases, test and fixes, presented at AIChE Annual Meeting, Minneapolis, MN, 30 October 2017. (talk)
88. S. Ravi, H. Narayanan and R. Gunawan. Metabolic network analysis for understanding the biology of ageing, presented at the 15th International Conference on Molecular Systems Biology, Raitenhaslach, DE, 26-28 July 2017. (poster)
87. H. Noh, Z. Hua and R. Gunawan, SALMON: A network analysis of transcriptomics data for inferring the molecular targets of compounds, presented at at 15th International Conference on Molecular Systems Biology, Raitenhaslach, DE, 26-28 July 2017. (selected winner of poster presentation prize)
86. R. Gunawan and S. Hutter. Model misspecifications in Metabolic Flux Analysis: Assessment and resolution, presented at 15th International Conference on Molecular Systems Biology, Raitenhaslach, DE, 27 July 2017. (talk)
85. S. Hutter, D. Lepori, M. Wolf, and R. Gunawan. Glycosylation flux analysis of mammalian perfusion cell culture, presented at 15th International Conference on Molecular Systems Biology, Raitenhaslach, DE, 27 July 2017. (talk)
84. H. Noh, J. Shoemaker and R. Gunawan. Identifying molecular targets of drugs using an integrative network analysis of molecular interactions and transcriptomics data, presented at Platform for Advanced Scientific Computing (PASC), Lugano, Switzerland, 28 June 2017. (winner of FOMICS PhD student prize)
83. N. Papili-Gao, S.M.M. Ud-Dean and R. Gunawan, Inferring gene regulatory networks from time-stamped single cell transcriptional expression profiles, presented at RECOMB, Hong Kong, China, 5 May 2017. (poster)
82. H. Noh, Z. Hua and R. Gunawan, Identifying molecular targets of drugs from gene transcriptional profiles, presented at RECOMB, Hong Kong, China, 5 May 2017. (poster)
81 S. Ravi and R. Gunawan. Bioinformatics analysis for understanding the biology of ageing, presented at the Genotype Tissue Expression (GTEx) Project Community Meeting, Barcelona, Spain, 21 April 2017.
80. S. Ravi and R. Gunawan, Metabolic network analysis for understanding the biology of ageing, presented at Drug Discovery Network Zurich, Zurich, Switzerland, 10 February 2017. (poster)
79. H. Noh, Z. Hua and R. Gunawan, Identifying molecular targets of drugs from gene transcriptional profiles, presented at Drug Discovery Network Zurich, Zurich, Switzerland, 10 February 2017. (poster)
78. Y. Liu and R. Gunawan. Bioprocess optimization under uncertainty using ensemble modeling, presented at AIChE Annual Meeting, San Francisco, CA, 16 November 2016. (talk)
77. S. Hutter, D. Karst, T. Schweigler, M. Morbidelli and R. Gunawan. Analyzing protein glycosylation in mammalian perfusion cell culture using glycosylation flux analysis, presented at AIChE Annual Meeting, San Francisco, CA, 16 November 2016. (talk)
76. N. Papili-Gao, S.M.M. Ud-Dean and R. Gunawan. Inferring gene regulatory networks from single cell expression data, presented at AIChE Annual Meeting, San Francisco, CA, 15 November 2016. (talk)
75. N. Vertti-Quintero, X. Casadevall i Solvas, O. Dressler, S. Stavrakis, J. Gruber, R. Gunawan and A. deMello, A microfluidic platform for the study and characterization of dynamic and stochastic expression of heat shock proteins in C. elegans, presented at Symposium Latsis, EPF Lausanne, Switzerland, 14 November 2016. (talk)
74. H. Noh, Z. Hua and R. Gunawan. Inferring molecular targets and mechanism of action from time course expression data, presented at 9th RECOMB/ISCB Conference on Regulatory and Systems Genomics, Phoenix, AZ, 7 November 2016. (talk)
73. H. Noh, Z. Hua and R. Gunawan. Inferring causal gene targets from time course expression data, presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering, Magdeburg, Germany, 12 October 2016. (talk)
72. N. Papili-Gao, S.M.M. Ud-Dean and R. Gunawan. Gene regulatory network inference using single cell expression data, presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering, Magdeburg, Germany, 10 October 2016. (poster)
71. R. Gunawan. Gene regulatory network inference using single cell expression data, presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering, Magdeburg, Germany, 10 October 2016. (keynote lecture)
70. LN. Lakshmanan, Z. Yee, J. Gruber, B. Halliwell and R.Gunawan, Deletion mutagenesis of mitochondrial DNA. In Cell Fate Diversity in Aging, Dubrovnik, Croatia, 25-28 September 2016. (poster)
69. N. Vertti-Quintero, X. Casadevall i Solvas, O. Dressler, S. Stavrakis, J. Gruber, R. Gunawan and A. deMello, A microfluidic platform for the study and characterization of intrinsic stochastic variability in the stress response system of C. elegans, presented at Microfluidics – EMBL Conference, Heidelberg, Germany, 24 June 2016. (poster and flash talk)
68. R. Gunawan, Coping with underdetermined biological network inference. In Platform for Advanced Scientific Computing, 9 June 2016. (talk)
67. H. Noh and R. Gunawan, Inferring causal gene targets from time course expression data. In SIB Days, Biel, Switzerland, 7-8 June 2016. (poster)
66. N. Papili-Gao and R. Gunawan, Gene regulatory network inference using cross-sectional single cell data. In SIB Days, Biel, Switzerland, 7-8 June 2016. (poster)
65. S. Hutter and R. Gunawan, Dynamic glycosylation flux analysis. In SIB Days, Biel, Switzerland, 7-8 June 2016. (poster)
64. S. Hutter, T. K. Villiger, D. Brühlmann, M. Stettler, H. Broly, M. Morbidelli, and R. Gunawan, Dynamic glycosylation flux analysis, presented at 6th Conference on Systems Biology of Mammalian Cells, Helmholtz Zentrum, Munich, Germany, 6-8 April 2016. (talk)
63. H. Noh and R. Gunawan, Inference targets of compounds from gene transcriptional profiles. In Systems Toxicology, Les Diablerets, Switzerland, 27-29 January 2016. (poster and flash talk)
62. H. Noh and R. Gunawan, Inference of Causal Gene Targets from Expression Data using DeltaNet, In the Drug Discovery Network Zurich Symposium, Zurich, Switzerland, 10 September, 2015. (poster)
61. H. Noh, J. Shoemaker, and R. Gunawan, Inference of Causal Gene Targets from Expression Data using DeltaNet, In the Foundations Of Systems Biology In Engineering Conference, Boston, MA, 9-12 August, 2015. (poster)
60. Y. Liu and R. Gunawan, Parameter Estimation of Dynamic Biological Network Models using Integrated Fluxes, In the 12th Basel Computational Biology Conference, Basel, Switzerland, June 7 - June 10, 2015. (poster)
59. S. M. Minhaz Ud-Dean and R. Gunawan, Design of Experiments for Causal Inference of Gene Regulatory Networks, In the 3rd Ascona Workshop on Statistical Learning of Biological Systems from Perturbations, Monte Verità, Ascona, Switzerland, 31 May-5 June 2015. (poster)
58. H. Noh and R. Gunawan, Inference of Causal Gene Targets from Expression Data, In the 3rd Ascona Workshop on Statistical Learning of Biological Systems from Perturbations, Monte Verità, Ascona, Switzerland, 31 May-5 June 2015. (poster)
57. LN. Lakshmanan and R. Gunawan, Thermodynamics Based Model Analysis of Deletion Mutagenesis in Mitochondrial DNA, In the 14th AIChE Annual Meeting, Atlanta, GA, November 16 – November 21, 2014. (oral presentation)
56. Y. Liu and R. Gunawan, Redemption: Reduced Dimensional Ensemble Modeling and Parameter Estimation, In the 14th AIChE Annual Meeting, Atlanta, GA, November 16 – November 21, 2014. (oral presentation)
55. S. Hutter and R. Gunawan, Analyzing Metabolic Shifts in Hybridoma Cells Using Dynamic Metabolic Flux Analysis Considering Network Uncertainty, In the 14th AIChE Annual Meeting, Atlanta, GA, November 16 – November 21, 2014. (oral presentation)
54. E. Manesso and R. Gunawan, A Bayesian Design of Experiments for Ensemble Modeling of Gene Regulatory Networks, Seventh Annual RECOMB/ISCB Conference on Regulatory and Systems Genomics, with DREAM Challenges and Cytoscape Workshops. San Diego, California, U.S.A., November 10-14, 2014. (oral presentation)
53. R. Gunawan, Direct Repeats and Deletions in Mitochondrial DNA: Causal and Evolutionary Aspects, SwissMito Meeting 2014, Kandersteg, Switzerland, 3 September 2014. (oral presentation)
52. S. M. Minhaz Ud-Dean and R. Gunawan, Ensemble Inference and Inferability of Gene Regulatory Networks, In RECOMB/ISCB Conference on Regulatory and Systems Genomics, with DREAM Challenges, Toronto, 8-12 November 2013. (oral presentation)
51. S. M. Minhaz Ud-Dean and R. Gunawan, Gene Regulatory Network Inference through Transitive Reduction and Closure Estimation, In Frontiers in Systems and Synthetic Biology, Atlanta, GA, 20-24 March 2013. (oral presentation)
50. C. Siegenthaler and R. Gunawan, Assessment of Network Inference Methods: How to cope with an underdetermined problem, In sbv IMPROVER Symposium, Athens, Greece, 29-31 October 2013. (poster)
49. G. Jia, G. Stephanopoulos and R. Gunawan, Incremental Parameter Estimation and Ensemble Kinetic Modeling of Metabolic Networks, In the 12th AIChE Annual Meeting, Pittsburgh, PA, October 28 – November 2, 2012. (oral presentation)
48. S. M. Minhaz Ud-dean and R. Gunawan, TRACE: Transitive Reduction and Closure Estimate of a Genetic Network, In Machine Learning in Systems Biology, Basel, Switzerland, September 2012. (poster)
47. S. M. Minhaz Ud-dean and R. Gunawan, TRACE: Transitive Reduction and Closure Estimate of a Genetic Network, In European Conference on Computational Biology, Basel, Switzerland, September 2012. (poster)
46. LN. Lakshmanan, J. Gruber, and R. Gunawan, Mitochondrial DNA Deletion Mutagenesis in Aging. In International Conference of Systems Biology, Toronto, Canada, August 2012. (poster)
45. G. Jia and R. Gunawan, Construction of Kinetic Model Library of Metabolic Networks, In the 12th International Symposium on Advanced Control of Chemical Processes, Singapore, July 2012. (oral presentation)
44. Z. Y. Tam, L. F. Ng, R. Gunawan and J. Gruber, Lithium Preserves Mitochondrial Function and Extend Healthspan in C. elegans, In the British Society for Research on Ageing Annual Meeting, Aston, UK, July 2012. (poster)
43. LN. Lakshmanan, J. Gruber, B. Halliwell and R. Gunawan, Role of Direct Repeats and DNA Misalignments in mtDNA Deletions: Cause or Coincidence? In Gordon Research Conference on Biology of Aging, Ventura, California, USA, February 2012. (poster)
42. T. M. Perumal and R. Gunawan, Dynamical Pathway Sensitivity Analysis for Biological Systems, In AIChE Annual Meeting, Minneapolis, Minnesota, October 2011. (oral presentation)
41. T. M. Perumal and R. Gunawan, Impulse Parametric Sensitivity Analysis, In the 18th World Congress of the International Federation of Automatic Control (IFAC), Milano, Italy, August 28 – September 2. 2011. (oral presentation)
40. Z. Y. Tam, J. Gruber, B. Halliwell and R. Gunawan, On the Roles of Mitochondrial Fusion-Fission in Mitochondrial Genome Integrity, In the 12th International Conference on Systems Biology, Mannheim, Germany, August 28 - September 1, 2011. (poster)
39. LN. Lakshmanan, J. Gruber, B. Halliwell and R. Gunawan, Mitochondrial DNA Deletions in Aging – Role of DNA Sequence Motifs. In the 12th International Conference on Systems Biology, Mannheim, Germany, August 28 - September 1, 2011. (poster)
38. G. Jia and R. Gunawan, Construction of Kinetic Model Library of Metabolic Networks from Dynamic Profiles, In the 12th International Conference on Systems Biology, Mannheim, Germany, August 28 - September 1, 2011. (poster)
37. LN. Lakshmanan, S. K. Poovathingal, and R. Gunawan, Modeling of Age-associated Mitochondrial DNA Deletions in Mouse Cardiac Tissue. In the Conference on Stochastic Systems Biology, Monte Verità, Switzerland, July 2011. (poster)
36. Z. Y. Tam, J. Gruber, B. Halliwell and R. Gunawan, On the Roles of Mitochondrial Fusion-Fission in Mitochondrial Genome Integrity, In the Conference on Stochastic Systems Biology, Monte Verità, Switzerland, July 2011. (poster)
35. LN. Lakshmanan, S. K. Poovathingal, and R. Gunawan, Mouse cardiac tissue modeling of age-associated deletions in mitochondrial genome. In The 8th Workshop in Computational System Biology, Zurich, Switzerland, June 2011. (poster)
34. S. Srinath and R. Gunawan, Model-based Design of Experiment for Kinetic Parameter Identification: Beyond the Fisher Information Matrix. In the 13th International Conference on Molecular Systems Biology, Lleida, Spain, May 2011.
33. G. Jia and R. Gunawan, Parameter Estimation of Kinetic Models from Metabolic Profiles: Two-phase Dynamic Decoupling Method, In the 13th International Conference on Molecular Systems Biology, Lleida, Spain, May 2011. (poster)
32. T. M. Perumal and R. Gunawan, Dynamical Model Reduction of Large Reaction Mechanisms: A Green’s Function Matrix (GFM) Based Approach. In AIChE Annual Meeting, Salt Lake City, UT, USA, November 2010.
31. T. M. Perumal and R. Gunawan, Caveats of Parametric Sensitivity Analysis (PSA): In analyzing the dynamics of biological systems. In AIChE Annual Meeting, Salt Lake City, UT, USA, November 2010.
30. S. K. Poovathingal, J. Gruber, B. Halliwell and R. Gunawan, Sarcopenia in silico. In AIChE Annual Meeting, Salt Lake City, UT, USA, November 2010.
29. S. K. Poovathingal, J. Gruber, B. Halliwell and R. Gunawan, Random Drift of Mitochondrial DNA Deletions in Sarcopenia, In 11th International Conference on Systems Biology, Edinburgh, UK, October 2010. (poster)
28. L. N. Lakshmanan, S. K. Poovathingal, J. Gruber, B. Halliwell and R. Gunawan, Elucidating Mechanisms of Age-dependent Accumulation of Mitochondrial DNA Deletions – An in silico Approach. In Gordon Research Conference on Biology of Aging, Les Diablerets, Switzerland, August 2010. (poster)
27. T. M. Perumal and R. Gunawan, In Analyzing the Complex Dynamics of Biochemical Pathways. In the satellite conference on Application of Control Theory and Optimization Techniques in Biochemical Pathways, HICC, Hyderabad, India, August 16-18, 2010.
26. S. Srinath and R. Gunawan, Parameter Identifiability of Metabolic Network Models, In Satellite Conference of the International Congress of Mathematics, Hyderabad, India, August 2010.
25. S. Srinath, Y. Zu and R. Gunawan, Identifiability Analysis of Decoupled Power-Law Models, In the 5th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia), Singapore, July 2010.
24. S. Srinath and R. Gunawan, Parameter Identifiability in Kinetic Modeling of Metabolic Pathways, In Metabolic Engineering Conference VIII, Jeju Island, South Korea, June 2010.
23. J. Gruber, S. K. Poovathingal, N. L. Fang, R. Gunawan and B. Halliwell, Deceptively simple – considerations regarding Caenorhabditis elegans lifespan, ageing and antioxidant studies. Strategies for Engineered Negligible Senescence (SENS-4), Cambridge, England, September 2009. (poster)
22. T.M. Perumal and R. Gunawan, Information transfer in biological network motifs. In 10th International Conference on Systems Biology, Stanford, CA, September 2009. (poster)
21. S. K. Poovathingal, J. Gruber, B. Halliwell and R. Gunawan, Stochasticity in mitochondrial DNA point mutations and its relevance in Caenorhabditis elegans aging. In 10th International Conference on Systems Biology, Stanford, CA, September 2009. (poster)
20. T.M. Perumal and R. Gunawan, Information theoretic global robustness analysis of cellular systems: a molecular perturbation approach. In Foundations of Systems Biology and Engineering (FOSBE), Denver, CO, August 2009. (poster)
19. S. K. Poovathingal and R. Gunawan. A Global Approach for Estimating the Kinetic Parameters of Stochastic Biological Systems. In Foundations of Systems Biology and Engineering (FOSBE), Denver, CO, August 2009. (poster)
18. S. Srinath and R. Gunawan. Identifiability analysis of metabolic networks. In Intl. Conf. of Molecular Systems Biology, Shanghai, PR China, July 2009.
17. K. S. Ang and R. Gunawan. Parameter estimation of oscillatory biological systems. In AIChE Annual Meeting, Philadelphia, PA, November 2008. (poster)
16. S. Poovathingal, J. Gruber, B. Halliwell, R. Gunawan. Aging Studies: A Stochastic Approach in point mutation dynamics in mouse model. In AIChE Annual Meeting, Philadelphia, PA, November 2008.
15. T. M. Perumal, Y. Wu, and R. Gunawan. Robustness analysis of cellular systems for in silico drug discovery. In IFAC World Congress, Seoul, South Korea, July 2008.
14. K. S. Ang and R. Gunawan. Parameter estimation for oscillatory biological systems. In Annual International Conference on Research in Computational Molecular Biology (RECOMB), Singapore, March 2008. (poster)
13. S. Poovathingal, J. Gruber, B. Halliwell, R. Gunawan. Aging studies: a stochastic approach. In Annual International Conference on Research in Computational Molecular Biology (RECOMB), Singapore, March 2008. (poster)
12. T. M. Perumal, Y. Wu, and R. Gunawan. In silico dynamical analysis of cellular systems: a molecular perturbation approach. In Annual International Conference on Research in Computational Molecular Biology (RECOMB), Singapore, March 2008. (poster)
11. T. M. Perumal, Y. Wu, and R. Gunawan. In silico dynamical analysis of cellular systems: a molecular perturbation approach. In 10th International Conference on Molecular Systems Biology, UP Dilliman, Quezon City, Philippines, February 2008. (poster)
10. T. M. Perumal, Y. Wu, and R. Gunawan. New in silico robustness analysis of cellular systems: a molecular perturbation approach. In 8th International Conference on Systems Biology, Long Beach, CA, October 2007. (poster)
9. R. Gunawan, S. R. Taylor, and F. J. Doyle III. Sensitivity analysis in biological modeling: an application in the model development of staphylococcal enterotoxin B response. In AIChE Annual Meeting, Cincinnati, OH, October 2005.
8. R. Gunawan and F. J. Doyle III. Isochron-based phase sensitivity analysis of biological oscillatory systems. In AIChE Annual Meeting, Cincinnati, OH, October 2005.
7. R. Gunawan, Y. Cao, L. Petzold, and F. J. Doyle III. Stochastic sensitivity analysis of discrete stochastic biological systems. In AIChE Annual Meeting, Austin, TX, November 2004.
6. R. Gunawan, Y. Cao, L. Petzold, and F. J. Doyle III. Stochastic sensitivity analysis of cellular processes. In Intl. Conf. of Molecular Systems Biology, Lake Tahoe, CA, August 2004.
5. R. Gunawan, I. Fusman, and R. D. Braatz. High resolution algorithms for multidimensional population balance equations with nucleation and size-dependent growth. In AIChE Annual Meeting, San Francisco, CA, November 2003.
4. R. Gunawan, M. Y. L. Jung, R. D. Braatz, and E. G. Seebauer. Systems analysis applied to modeling transient enhanced diffusion. AIChE Annual Meeting, Indianapolis, IN, November 2002.
3. R. Gunawan, M. Y. L. Jung, E. G. Seebauer, and R. D. Braatz. Optimal control of transient enhanced diffusion. AIChE Annual Meeting, Indianapolis, IN, November 2002.
2. R. Gunawan, M. Y. L. Jung, E. G. Seebauer, and R. D. Braatz. Maximum a posteriori estimation of transient enhanced diffusion kinetics. AIChE Annual Meeting, Indianapolis, IN, November 2002.
1. R. Gunawan, D. L. Ma, M. Fujiwara, and R. D. Braatz. Identification of kinetic parameters in a multidimensional crystallization process. Int. Conf. on Materials for Advanced Technologies, Symposium D: Crystallization and Interfacial Processes, Singapore, July 2001. (poster)